Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Leukemia
  •  Central Nervous System Tumors
  •  Radiological Techniques and Scans
  •  Endometrial Cancer
  •  Stomach Cancer
  •  Pancreatic Cancer
  •  Head and Neck Oncology
  •  Chemotherapy and Radiotherapy


Citation: Clin Oncol. 2021;6(1):1855.DOI: 10.25107/2474-1663.1855

The Psychological Impact on 472 Gynecological Cancer Patients: First Diagnosis vs. Disease Recurrence

Daniela Pia Rosaria Chieffo, Letizia Lafuenti, Ludovica Mastrilli, Barbara Costantini, Silvia Riccardi, Gabriella Ferrandina, Vanda Salutari, Francesco Fanfani, Giovanni Scambia and Anna Fagotti

Agostino Gemelli University Policlinic, IRCCS, Italy
Fondazione Umberto Veronesi, Italy
Department of Woman and Child Health and Public Health, Agostino Gemelli University Policlinic, IRCCS, Italy
Catholic University of the Sacred Heart, Italy
Clinical Psychology Unit, Santo Spirito Hospital, Italy

*Correspondance to: Daniela Pia Rosaria Chieffo 

 PDF  Full Text Research Article | Open Access


Objective: The diagnosis of gynecological cancer, or its recurrence, is often reflected in dramatic changes in a woman's life, and in her family too. The level of emotional distress associated with cancer treatment varies greatly at different stages of the treatment pathway and is determined not only by the severity of the clinical symptoms, but also by the therapeutic outcome and a number of individual psychological characteristics.
This study aims to assess the difference in the psychological impact of the diagnosis of recurrence compared to the first diagnosis, in patients with gynecological cancer, comparing distress, anxiety, and depression scores.
Method: Four hundred seven women with gynecological cancer who were admitted to the Female Tumors Day Hospital or oncological gynecology ward of Policlinico Universitario Agostino Gemelli Foundation IRCCS were recruited. All patients completed questionnaires to assess distress, anxiety and depression at T0 on the admission.
Results: It was observed that group of patients with recurrence scored higher than the group with the first diagnosis, in all three scales: distress (p=0.000), anxiety (p=0.000) and depression (p=0.000).
Conclusion: Our findings show that patients with recurrence have obtained statistically higher scores in all three scales administered to assess distress, anxiety and depression. In line with other study, these results indicate that recurrence has a worse psychological impact on patients.


Anxiety; Cancer; Depression; Emotional distress; Female tumor; First diagnosis; Gynecology; Oncology; Psycho-oncology; Recurrence

Cite the Article:

Chieffo DPR, Lafuenti L, Mastrilli L, Costantini B, Riccardi S, Ferrandina G, et al. The Psychological Impact on 472 Gynecological Cancer Patients: First Diagnosis vs. Disease Recurrence. Clin Oncol. 2021;6:1855..

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