Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Breast Cancer
  •  Central Nervous System Tumors
  •  Chemotherapy and Radiotherapy
  •  Gastrointestinal Cancer
  •  Neoadjuvant Therapy
  •  Adjuvant Therapy
  •  Pancreatic Cancer
  •  Colon Cancer


Citation: Clin Oncol. 2020;5(1):1694.DOI: 10.25107/2474-1663.1694

Roles of Histone Modifications in Gastrointestinal Tumorigenesis

Jing Liu and Li Li

Department of Medicine and Stem Cell Research, Shanghai Jiao Tong University, Shanghai, China

*Correspondance to: Li Li 

 PDF  Full Text Review Article | Open Access


Histone modifications play important roles in gastrointestinal tumorigenesis as tumor suppressors or oncogenic drivers depending on the type of tumor and histone modification. The diversity of histone modifications leads to a remarkable complexity in the functions and mechanisms they regulate, which are gradually beginning to be elucidated. This review concentrates on current research regarding the roles of histone modifications and associated histone-modifying enzymes in gastrointestinal tumorigenesis


Histone modification; Tumorigenesis; Epigenetics

Cite the Article:

Liu J, Li L. Roles of Histone Modifications in Gastrointestinal Tumorigenesis. Clin Oncol. 2020; 5: 1694.

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