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Abstract
Citation: Clin Oncol. 2020;5(1):1694.DOI: 10.25107/2474-1663-v5-id1694
Roles of Histone Modifications in Gastrointestinal Tumorigenesis
Jing Liu and Li Li
Department of Medicine and Stem Cell Research, Shanghai Jiao Tong University, Shanghai, China
PDF Full Text Review Article | Open Access
Abstract:
Histone modifications play important roles in gastrointestinal tumorigenesis as tumor suppressors or oncogenic drivers depending on the type of tumor and histone modification. The diversity of histone modifications leads to a remarkable complexity in the functions and mechanisms they regulate, which are gradually beginning to be elucidated. This review concentrates on current research regarding the roles of histone modifications and associated histone-modifying enzymes in gastrointestinal tumorigenesis
Keywords:
Histone modification; Tumorigenesis; Epigenetics
Cite the Article:
Liu J, Li L. Roles of Histone Modifications in Gastrointestinal Tumorigenesis. Clin Oncol. 2020; 5: 1694.
Journal Basic Info
- Impact Factor: 3.231**
- H-Index: 11
- ISSN: 2474-1663
- DOI: 10.25107/2474-1663
- PubMed NLM ID: 101705590
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