Journal Basic Info
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.Major Scope
- Lymphoma
- Sarcomas
- Radiation Therapy
- Gynecological Cancers
- Endometrial Cancer
- Head and Neck Oncology
- Radiological Techniques and Scans
- Stomach Cancer
Abstract
Citation: Clin Oncol. 2017;2(1):1292.DOI: 10.25107/2474-1663-v2-id1292
A Rare Case of Spindle Cell Sarcoma Presenting as a Recurrent Breast Cyst
Boris Hristov and Saptarshi Biswas
Department of Acute Care Surgery, Forbes Regional Hospital, Pennsylvania, USA
*Correspondance to: Saptarshi Biswas
PDF Full Text Case Report | Open Access
Abstract:
Primary sarcomas of the breast are rare neoplasms which comprise between 0.2%-1.0% of all breast malignancies. They often carry a poor prognosis with mortality rates greater than 40%. In addition, these malignancies can be difficult to diagnose in a timely fashion as they can mimic other benign breast pathologies such as cysts. Here we present a case of a primary spindle cell carcinoma of the breast in a 53 year old female with fibrocystic breast disease which presented as a recurrent large breast cyst. Although she underwent a cyst aspiration and a FNA biopsy of her breast lesion during outpatient visits the results of both were negative for malignancy. Following suspicious mammography findings the patient underwent a breast cyst resection. A diagnosis of a high grade spindle cell sarcoma was made after immunohistochemical analysis showed a tumor in the wall of the cyst staining positive with Vimentin, Smooth Muscle Antigen (SMA) and Ki-67 as well as focal positive staining with S100, CD 68, p63. Despite undergoing a completion mastectomy and resection of the pectoralis major the patient’s sarcoma recurred one month later and she subsequently refused further treatment. We have illustrated a rare case of primary spindle cell sarcoma of the breast which presented as a recurrent breast cyst that had a negative cytology as well as a negative FNA. Clinicians should be aware of such atypical presentations as delays in diagnosis can contribute to the mortality rates of this rare but aggressive malignancy.
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Cite the Article:
Hristov B, Biswas S. A Rare Case of Spindle Cell Sarcoma Presenting as a Recurrent Breast Cyst. Clin Oncol. 2017; 2: 1292.