A Rare Case of Spindle Cell Sarcoma Presenting as a Recurrent Breast Cyst

Boris Hristov and Saptarshi Biswas

Department of Acute Care Surgery, Forbes Regional Hospital, Pennsylvania, USA

^*Correspondance to: Saptarshi Biswas 

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Abstract:

Primary sarcomas of the breast are rare neoplasms which comprise between 0.2%-1.0% of all breast malignancies. They often carry a poor prognosis with mortality rates greater than 40%. In addition, these malignancies can be difficult to diagnose in a timely fashion as they can mimic other benign breast pathologies such as cysts. Here we present a case of a primary spindle cell carcinoma of the breast in a 53 year old female with fibrocystic breast disease which presented as a recurrent large breast cyst. Although she underwent a cyst aspiration and a FNA biopsy of her breast lesion during outpatient visits the results of both were negative for malignancy. Following suspicious mammography findings the patient underwent a breast cyst resection. A diagnosis of a high grade spindle cell sarcoma was made after immunohistochemical analysis showed a tumor in the wall of the cyst staining positive with Vimentin, Smooth Muscle Antigen (SMA) and Ki-67 as well as focal positive staining with S100, CD 68, p63. Despite undergoing a completion mastectomy and resection of the pectoralis major the patient’s sarcoma recurred one month later and she subsequently refused further treatment. We have illustrated a rare case of primary spindle cell sarcoma of the breast which presented as a recurrent breast cyst that had a negative cytology as well as a negative FNA. Clinicians should be aware of such atypical presentations as delays in diagnosis can contribute to the mortality rates of this rare but aggressive malignancy.

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Cite the Article:

Hristov B, Biswas S. A Rare Case of Spindle Cell Sarcoma Presenting as a Recurrent Breast Cyst. Clin Oncol. 2017; 2: 1292.