Influence of Sex Hormones in the Progression of Oral Cancer

Sivaperumal P, Kamala K and Dilipan E

Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, India
Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, India

^*Correspondance to: Kannan Kamala 

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Abstract:

The imbalance of hormones causes different health problems including diabetes, obesity, cancer, heart disease etc. Sex hormones are playing vital role in transcription by their binding capacity on DNA and responsible for the pathogenesis in salivary duct carcinoma and other cancers. Aromatase (AR) and androgen has affected the apoptotic factors (bcl-2) and improves the proto-oncogenes (C-myc). But the role of sex hormones on oral cancer was unknown. Also, the hormone estrogen and progesterone receptors and their up regulations were not yet reported in oral cancer patients. Therefore, the present commentary is focused to cover on sex hormone influences in oral cancer and their diagnosis at early stages.

Keywords:

Sex hormone; Oral cancer; Apoptotic factors (bcl-2); FSH; LH

Cite the Article:

Sivaperumal P, Kamala K, Dilipan E. Influence of Sex Hormones in the Progression of Oral Cancer. Clin Oncol. 2022;7:1961..