Long-Term Survival of Large (≥3CM) Hepatocellular Carcinoma Treated with Microwave Ablation

Haokang Wei, Simon Chivi and Sohail Contractor

Department of Radiology, Rutgers New Jersey Medical School, USA

^*Correspondance to: Sohail Contractor 

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Abstract:

Purpose: To evaluate the long‐term Overall Survival (OS) rate in patients with large (≥3cm) Hepatocellular Carcinoma (HCC) treated with Microwave Ablation (MWA).Materials and
Methods: 19 patients with HCC with tumors size ranging from 3cm-9.5cm were treated with MWA. 15 of the 19 patients had single tumor, 4 patients had multiple tumors. 23 tumors were identified. Lesions were evaluated at 1-, 3‐, and 6-months post ablation using the mRECIST criteria. 12 of the 19 patients had Transhepatic Arterial Chemoembolization (TACE), 8 patients had repeat MWA, and 3 patients had liver transplant subsequently. OS rate was analyzed.Result: The mean follow up period was 22.8 ± 12.8 months, and the range was 2-40 months by the end of study. Out of 23 tumors, 10 tumors had Partial Response (PR), 8 tumors had Complete Response (CR), 3 tumors had Stable Disease (SD), and 2 tumors had Progressive Disease (PD). The 6-month, 1-year and 2-year OS rates were 94.4%, 94.4%, and 85.7% respectively.
Conclusion: MWA is an effective treatment for HCC ≥3cm given its favorable long-term OS rate.

Keywords:

Microwave ablation; Large hepatocellular carcinoma; Long-term survival

Cite the Article:

Wei H, Chivi S, Contractor S. Long- Term Survival of Large (≥3CM) Hepatocellular Carcinoma Treated with Microwave Ablation. Clin Oncol. 2017; 2: 1294.