Acute Esophageal Necrosis Complicated by Severe Upper Gastrointestinal Bleeding in Association with Bosutinib Treatment for Chronic Myelogenous Leukemia

Danah Mohammad, Anwar Albasri, Jeff Lipton and Michael Beyak

Department of Medicine, Queens University, Kingston, ON, Canada
Department of Medical Oncology and Hematology, University of Toronto, Toronto, Canada

^*Correspondance to: Jeff Lipton 

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Abstract:

Acute Esophageal Necrosis (AEN), also known as “Black Esophagus”, is a rare life threatening condition with unknown cause. We present a case of AEN in an 82 years-old male on Tyrosine Kinase Inhibitor (TKI) for Chronic Myelogenous Leukemia (CML). While TKI is known to cause GI toxicity, this is the first case, to our knowledge, reporting AEN.

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Cite the Article:

Mohammad D, Albasri A, Lipton J, Beyak M. Acute Esophageal Necrosis Complicated by Severe Upper Gastrointestinal Bleeding in Association with Bosutinib Treatment for Chronic Myelogenous Leukemia. Clin Oncol. 2017; 2: 1266.