Journal Basic Info

  • Impact Factor: 3.231**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Melanoma/Skin Cancer
  •  Palliative Care
  •  Endometrial Cancer
  •  Gynecological Cancers
  •  Surgical Oncology
  •  Head and Neck Oncology
  •  Radiation Oncology
  •  Colon Cancer

Abstract

Citation: Clin Oncol. 2024;9(1):2118.DOI: 10.25107/2474-1663-v9-id2118

Transtubal Spread of Endocervical Adenocarcinomas: An Unnoticed Mechanism of Metastasis

Vieira Breijão AO, Ramos Alecrim AA, Bueno Torres RA, Chacara GM, Olibeira Costa GD, Alves Cardoso CM and Souza Viana LD

Department of Oncology, Marcio Cunha Hospital, Fundação São Francisco Xavier, Brazil These authors contributed equally to this work

*Correspondance to: Luciano de Souza Viana 

 PDF  Full Text Case Report | Open Access

Abstract:

We report the case of a 49-year-old woman with isolated, unilateral, ovarian metastasis of endocervical adenocarcinoma in situ four years after undergoing total hysterectomy. Extensive workup (including colonoscopy and upper endoscopy) excluded other sites of active disease. Histopathology review confirmed the absence of an invasive component of endocervical adenocarcinoma and both tumor samples had the same histological characteristics and were P16positive tumors by immunohistochemistry analysis, supporting the interpretation of the ovarian neoplasms as a late recurrent of endocervical adenocarcinomas, simulating primary ovarian surface epithelial neoplasms. The patient underwent bilateral oophorectomy with complete tumor resection, followed by six cycles of chemotherapy. The patient remains alive with no evidence of disease after seven years of follow-up. The lack of recognizable stromal invasion, absence of lymph node involvement, and distal organ metastasis make transtubal spread the most likely route of dissemination in this presented case, and it might not result in an adverse outcome.

Keywords:

Endocervical adenocarcinoma; Ovarian metastasis; p16-positive

Cite the Article:

Vieira Breijão AO, Ramos Alecrim AA, Bueno Torres RA, Chacara GM, Olibeira Costa GD, Alves Cardoso CM, et al. Transtubal Spread of Endocervical Adenocarcinomas: An Unnoticed Mechanism of Metastasis. Clin Oncol. 2024; 9: 2118..

Search Our Journal

Journal Indexed In

Articles in PubMed

NMR Metabolomics in Ionizing Radiation
 PubMed  PMC  PDF  Full Text
LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Gene Polymorphisms and Gene Expression Profiles as Potential Predictors of Survival Outcomes in Ovarian Cancer: Systematic Review and Meta-Analysis of Pharmacogenetic/Genomic and Microarray Data
 Abstract  PDF  Full Text
Synchronous Double Primary Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: A Case Report and Review of the Literature
 Abstract  PDF  Full Text
View More...