
Journal Basic Info
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.Major Scope
- Melanoma/Skin Cancer
- Palliative Care
- Endometrial Cancer
- Gynecological Cancers
- Surgical Oncology
- Head and Neck Oncology
- Radiation Oncology
- Colon Cancer
Abstract
Citation: Clin Oncol. 2024;9(1):2118.DOI: 10.25107/2474-1663-v9-id2118
Transtubal Spread of Endocervical Adenocarcinomas: An Unnoticed Mechanism of Metastasis
Vieira Breijão AO, Ramos Alecrim AA, Bueno Torres RA, Chacara GM, Olibeira Costa GD, Alves Cardoso CM and Souza Viana LD
Department of Oncology, Marcio Cunha Hospital, Fundação São Francisco Xavier, Brazil These authors contributed equally to this work
*Correspondance to: Luciano de Souza Viana
PDF Full Text Case Report | Open Access
Abstract:
We report the case of a 49-year-old woman with isolated, unilateral, ovarian metastasis of endocervical adenocarcinoma in situ four years after undergoing total hysterectomy. Extensive workup (including colonoscopy and upper endoscopy) excluded other sites of active disease. Histopathology review confirmed the absence of an invasive component of endocervical adenocarcinoma and both tumor samples had the same histological characteristics and were P16positive tumors by immunohistochemistry analysis, supporting the interpretation of the ovarian neoplasms as a late recurrent of endocervical adenocarcinomas, simulating primary ovarian surface epithelial neoplasms. The patient underwent bilateral oophorectomy with complete tumor resection, followed by six cycles of chemotherapy. The patient remains alive with no evidence of disease after seven years of follow-up. The lack of recognizable stromal invasion, absence of lymph node involvement, and distal organ metastasis make transtubal spread the most likely route of dissemination in this presented case, and it might not result in an adverse outcome.
Keywords:
Endocervical adenocarcinoma; Ovarian metastasis; p16-positive
Cite the Article:
Vieira Breijão AO, Ramos Alecrim AA, Bueno Torres RA, Chacara GM, Olibeira Costa GD, Alves Cardoso CM, et al. Transtubal Spread of Endocervical Adenocarcinomas: An Unnoticed Mechanism of Metastasis. Clin Oncol. 2024; 9: 2118..