Low Grade Osteosarcoma of Zygomatic and Orbital Bones in 7 Years Old Girl: A Challenge for Diagnosis and Management. First Case Report

Hegab AF, Ramzy NIA, Hyder A and Shahin M

Department of Oral & Maxillofacial Surgery, Al-Azhar University in Cairo, Egypt
Department of Pathology, Cairo University, Egypt
Oral & Maxillofacial Surgery, Menouf General Hospital, Egypt

^*Correspondance to: Ayman F Hegab 

 PDF  Full Text Case Report | Open Access

Abstract:

Low grade osteosarcoma of the facial bone is an exceedingly rare pathology in the pediatric population. To our knowledge, this is the first case report of a 7-year-old girl with low grade osteosarcoma of zygomatic and orbital bones. Low grade osteosarcoma is unfamiliar to clinicians, radiologists, and pathologists. Radiological diagnosis is challenging, and low-grade osteosarcoma typically simulates benign bone disease but with some aggressive features. However, if it is properly diagnosed, there is a high chance of a cure with wide excision alone. Positive immunostaining for MDM2 may be used as a diagnostic adjunct, although negative immunostaining cannot rule out this tumor. The clinical, radiological, and typical pathological findings are vital in raising the suspicion of this rare tumor. To our records; the current case report is the first case report of Low-grade osteosarcoma of zygomatic and orbital bones in 7 years old girl.

Keywords:

Low grade osteosarcoma; Zygomatic bone; Orbital bone; MDM2; Computer-aided design/computer-aided manufacturing; Cranio-maxillofacial defect; Reconstructive surgical procedures

Cite the Article:

Hegab AF, Ramzy NIA, Hyder A, Shahin M. Low Grade Osteosarcoma of Zygomatic and Orbital Bones in 7 Years Old Girl: A Challenge for Diagnosis and Management. First Case Report. Clin Oncol. 2024;9:2089..