Primary Malignant Pulmonary Glomus Tumor: A Case Report and Literature Review

Luo S, Fu T1, Liu F and Wang Z

Department of Radiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), P. R. China
Department of Pathology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), P. R. China
Department of Radiology, Hainan Hospital of Traditional Chinese Medicine, China

^*Correspondance to: Zhenping Wang 

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Abstract:

Malignant glomus tumors originating from the lungs are relatively rare. Here, we report a case of primary malignant pulmonary glomus tumor. The patient was a 41-year-old female. Chest CT revealed an 8 cm × 6 cm mass in the upper lobe of the right lung with multiple spotted calcifications and uneven enhancement on enhanced scans. Multiple metastatic nodules were seen in both lungs, and enlarged lymph nodes were observed in the mediastinum and right hilar lobe. The pathological diagnosis after right lung puncture was malignant pulmonary glomus tumor. Chemotherapy and targeted therapy with arotinib hydrochloride were used, and the patient was still alive after 36 months of follow-up. The clinical manifestations of primary malignant pulmonary glomus tumor lack specificity. The imaging manifestations are well-defined nodules or masses, with peripheral enhancement on enhanced scans. The imaging manifestations of benign and malignant pulmonary glomus tumors overlap with those of other lung tumors, making differential diagnosis difficult. The diagnosis is mainly based on pathology and immunohistochemical staining.

Keywords:

Glomus tumor; Pulmonary; Malignant; Computed tomography

Cite the Article:

Luo S, Fu T, Liu F, Wang Z. Primary Malignant Pulmonary Glomus Tumor: A Case Report and Literature Review. Clin Oncol. 2024;9:2076..