Case Report of Three Saudi Pediatric and Adolescent Patients with Poorly Differentiated Thyroid Cancer: A Unique and Challenging Entity

Alhejaily AMG, Alaybaa KH, Alatawi JA, Al Ghamdi DA, Alghofely M, Aljohani NJ and Alhuzaim ON

Department of Basic Medical Science, King Fahad Medical City, Riyadh Second Health Cluster, KSA
Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh Second Health Cluster, KSA
Department of Anatomical Pathology, and Pathology, King Fahad Medical City, Riyadh Second Health Cluster, KSA
Department of Pediatric Endocrinology, Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh Second Health Cluster, KSA
Collage of Medicine, Alfaisal University, KSA

^*Correspondance to: Omar Nasser Alhuzaim 

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Abstract:

Poorly Differentiated Thyroid Cancer (PDTC) is an infrequent and aggressive form of thyroid malignancy, characterized by histological features that lie between those of well-differentiated and anaplastic thyroid cancers. PDTC in pediatric and adolescence is even more rare and its clinical manifestations, histological features and outcomes are not well known. This case series of pediatric and adolescent PDTC provides a comprehensive examination of the clinical manifestation, diagnostic challenges, therapeutic approaches, and outcomes linked to PDTC, as shown by three unique cases from a single tertiary care center in Saudi Arabia.

Keywords:

Thyroid cancer; Poorly differentiated thyroid cancer; Clinical management; Prognosis

Cite the Article:

Alhejaily AMG, Alaybaa KH, Alatawi JA, Al Ghamdi DA, Alghofely M, Aljohani NJ, et al. Case Report of Three Saudi Pediatric and Adolescent Patients with Poorly Differentiated Thyroid Cancer: A Unique and Challenging Entity. Clin Oncol. 2023;8:2039..