Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Thoracic Oncology
  •  Chemotherapy and Radiotherapy
  •  Cervical Cancer
  •  Prostate Cancer
  •  General Oncology
  •  Radiological Techniques and Scans
  •  Endometrial Cancer
  •  Chemoprevention

Abstract

Citation: Clin Oncol. 2022;7(1):1976.DOI: 10.25107/2474-1663.1976

Clinico-Endoscopic and Histopathological Profile of Gastric Cancer Patients in Southern Kashmir, India

Romshoo GJ, Jeelani U and Ul Unsa H

Department of Medicine, Government Medical College, Jammu and Kashmir, India
Department of Radiation Oncology, Government Medical College, Jammu and Kashmir, India
Internee, Tairunissa Memorial Medical College, Bangladesh

*Correspondance to: Ubaid Jeelani 

 PDF  Full Text Research Article | Open Access

Abstract:

Aim: To determine the clinical, endoscopic and histopathological profile of gastric cancer patients of a high-risk region of southern Kashmir, India.
Methods: This retrospective multi-centric study of 18 years (2001-2019) was carried out at three different government district hospitals of southern Kashmir located at Anantnag, Shopian, and Kulgam and comprised 1,433 Gastric Cancer (GC) patients with 1,025 males and 408 females who were in the age group of 38 to 80 years. These cancers were diagnosed by performing
Esophagogastroduodenoscopy (EGD). Six to eight tissue bits were taken from gastric cancer growths and subjected to histopathological examination for confirmation of endoscopic diagnosis.
Results: Out of 1,433 gastric cancer patients there were 1,025 (72%) males and 408 (28%) females. The major clinical presentation in these patients was anorexia (69.08%), anemia (62.10%), and postprandial fullness (48.7%). Forty-five patients presented with metastasis. Lesser curvature was the most common site for gastric cancers (68.1%) followed by pylorus (23.72%). Helicobacter pylori (H. pylori) was found in 35.38% of gastric cancers. Endoscopically majority of the gastric cancers were polypoid type (63.56%) followed by ulcerative type (33.44%). Histopathologically majority of the gastric cancers were intestinal type of adenocarcinomas.
Conclusion: Kashmir Valley especially its Southern part is emerging as a highly prevalent gastric cancer region. These cancers have peculiar endoscopic and histopathological patterns. Although the exact etiopathology of these cancers and their high prevalence is largely unknown yet the unique personal and dietary habits, socioeconomic conditions, genetic characteristics, and other unknown factors have an important role in the pathogenesis of these cancers.

Keywords:

Adenocarcinoma; Gastric cancer; H pylori; Histopathology

Cite the Article:

Romshoo GJ, Jeelani U, Ul Unsa H. Clinico-Endoscopic andHistopathological Profile of Gastric Cancer Patients in Southern Kashmir, India. Clin Oncol. 2022;7:1976..

Search Our Journal

Journal Indexed In

Articles in PubMed

Metastatic Retroperitoneal Paraganglioma: Case Report and Review of the Literature
 PubMed  PMC  PDF  Full Text
NMR Metabolomics in Ionizing Radiation
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Hepatic Arterial Infusion Chemotherapy vs. Transcatheter Arterial Embolization for Patients with Huge Unresectable Hepatocellular Carcinoma
 Abstract  PDF  Full Text
Ezrin Intracellular Cytoskeleton Marker is Over Expressed in Pancreatic Ductal Adenocarcinoma: A Prospective Cohort Study
 Abstract  PDF  Full Text
View More...