Clin Oncol | Volume 7, Issue 1 | Case Report | Open Access

Toothache and Lymphoma in the Mandible: Case Report of a Diagnostic Challenge and Management

Letícia Mello Bezinelli1, Fernanda de Paula Eduardo1*, Mariana Henriques Ferreira1, Nelson Hamerschlak1 and Cesar Augusto Migliorati2

1Hospital Israelita Albert Einstein, Brazil
2Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, USA

*Correspondance to: Fernanda de Paula Eduardo 

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This case report discusses a case of a patient with past history of Non-Hodgkin’s Lymphoma (NHL) who developed pain and paresthesia in the oral cavity associated with a tooth. The close collaboration between the oral medicine providers and the oncologists, lead to the diagnosis of a relapse of NHL, not only in the oral cavity but other body sites. The management of the case with chemotherapy leads to the elimination of the pain and paresthesia in the mouth and the resolution of all relapsed
lesions without the need to perform a dental extraction of the involved tooth.


Lymphoma; Paresthesia symptoms; DLBCL; NHL


Bezinelli LM, de Paula Eduardo F, Ferreira MH, Hamerschlak N, Migliorati CA. Toothache and Lymphoma in the Mandible: Case Report of a Diagnostic Challenge and Management. Clin Oncol. 2022;7:1925..

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