Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Bladder Cancer
  •  Neoadjuvant Therapy
  •  Palliative Care
  •  Sarcomas
  •  Lymphoma
  •  Stomach Cancer
  •  Prostate Cancer
  •  Targeted Therapy


Citation: Clin Oncol. 2020;5(1):1695.DOI: 10.25107/2474-1663.1695

Phlegmon Formation as an Unforeseen Complication Following Radiotherapy of the Hypopharynx

Michelle Misri, Karina Awdi and Małgorzata Leszczyńska

Department of Otolaryngology, Poznan University of Medical Sciences, Poland

*Correspondance to: Michelle Misri 

 PDF  Full Text Case Report | Open Access


Phlegmon is an extremely rare and usually unforeseen complication in patients with malignant neoplasms, who undergo radiotherapy. The condition is usually of a bacterial origin and its formation may be precipitated by an impaired immune system. In this case report, we present a 54-year-old male who has undergone radiotherapy treatment for squamous cell carcinoma in the tonsil-lingual angle. Four months later, the patient developed radionecrosis with subsequent edema, bleeding, epithelial changes, as well as signs of acute infection that rapidly spread from neck to chest and the stomach. Ultimately, the patient has been diagnosed with radionecrosis and phlegmon complicated by radiotherapy and poor health status. Our primary interest was to investigate why the patient has developed a phlegmon, as this is a very atypical consequence following radiotherapy. We refer to the literature to determine if a similar case has been reported in the head and neck area. We suspect that the etiology related to the radiation therapy is complicated by the patient’s compromised immune system.


Radionecrosis; Phlegmon; Oncology

Cite the Article:

Misri M, Awdi K, Leszczyńska M. Phlegmon Formation as an Unforeseen Complication Following Radiotherapy of the Hypopharynx. Clin Oncol. 2020; 5: 1695.

Search Our Journal

Journal Indexed In

Articles in PubMed

NMR Metabolomics in Ionizing Radiation
 PubMed  PMC  PDF  Full Text
LINGO-1 is a New Therapy Target and Biomarker for Ewing Sarcoma
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Achillea fragrantissima: Pharmacology Review
 Abstract  PDF  Full Text
Bovine Milk Derived Exosomal - Curcumin Exhibiting Enhanced Stability, Solubility, and Cellular Bioavailability
 Abstract  PDF  Full Text
View More...