Pattern and Age Distribution of Leukemia in Sudan-Retrospective Analysis

Amar A Dowd, Salah OM

Department of Hematology, University of Medical Science and Technology, Sudan
Sudan Radioisotope Center, Sudan

^*Correspondance to: Amar A Dowd 

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Abstract:

Low income countries in sub-Saharan Africa are experiencing a rapidly growing cancer burden, and leukemia account for 6.9% of death rate from cancer in the region. So far there are no comprehensive descriptions reporting of diagnosed leukemia in Sudan. This is a hospital based retrospective descriptive study (RICK) from 2009 till 2013. The main aim of this study is to reflect the burden of hematological cancer and the epidemiological data based on the demographic characteristic (age, sex, and frequency of hematological cancer). Morphological typing was done according to FAB classification. Result reveal total of 2535 registered patients aged between 1 to 97 years had been diagnosed with malignant hematological disorder (Leukemia). A 58.1% were male (n=1474) and 41.9% (n=1061) were female with male to female ratio of 1.3 to 1.0. The overall mean age at diagnosis was 40 years. Chronic myeloid leukemia was the most frequent (32.3%) with the mean age of 44.5 years followed by AML 42.8% mean age of 35.1 years, ALL represent 21.1% with the mean age 19.3 while CLL 21.7% with mean age 60.8. This study presents the pattern and distribution of leukemia. It shows the differences in the population as compared to other settings with lower prevalence of CLL and ALL, women might be under reported. Further genetic and epidemiological study is highly recommended.

Keywords:

Leukemia; French American British; Acute lymphoblastic leukemia; Acute myeloid leukemia; Chronic myeloid leukemia

Cite the Article:

Dowd AA, Salah OM. Pattern and Age Distribution of Leukemia in Sudan-Retrospective Analysis. Clin Oncol. 2020;5:1679.