Is Mycosis Fungoides Truly an Indolent Pathology?

Sabah Bazouti, Said Afqir, Nada Zizi, Siham Dikhaye

Department of Dermatology, Mohammed 6 University Hospital of Oujda – Medical School of Oujda, Mohammed the First University of Oujda, Morocco
Laboratory of Epidemiology, Clinical Research and Public Health, Medical School of Oujda, Mohammed the First University of Oujda, Morocco
Department of Oncology, Mohammed 6 University Hospital of Oujda – Medical School of Oujda, Mohammed the First University of Oujda, Morocco

^*Correspondance to: Sabah Bazouti 

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Abstract:

The course of Mycosis Fungoides (MF) is indolent except when the transformation to a large T-cell lymphoma occurs. The diagnosis of transformed MF relies on the presence of more than 25% of large cells on biopsy of an MF lesion. Treatment of transformed MF is a major challenge as these patients have poor outcome. Here, we report a 40-year-old man presenting in an advanced stage of disease with nodules all over the body diagnosed as cutaneous CD30(−) large cell transformed MF of fatal evolution.

Keywords:

Cutaneous T-cell lymphomas; Transformed mycosis fungoides; Tumor stage; CD30-

Cite the Article:

Bazouti S, Afqir S, Zizi N, Dikhaye S. Is Mycosis Fungoides Truly an Indolent Pathology? Clin Oncol. 2019; 4: 1565.