Solid Pseudo-Papillary Tumor of Pancreas - A Rare Case Report

Sood N and Jindal Y

Department of Pathology, Deen Dayal Upadhyay Hospital, India

^*Correspondance to: Jindal Y 

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Abstract:

Solid Pseudopapillary Tumor (SPPT) of the pancreas is a rare tumor accounting for 1% to 3% of exocrine pancreatic neoplasm. It typically affects mostly young women, often in their 20’s. Present case is of 28 years old female patient with complaint of abdominal pain. Her radiological investigation showed large retroperitoneal mass, measuring 10 cm × 9 cm × 8 cm with multiple small central? Necrotic foci origin of this mass could not be ascertained. FNA done from retroperitoneal mass under USG-guidance showed few atypical cells in clusters and scattered singly. These cells showed moderate anisonucleosis, indistinct nucleoli and abundant cytoplasm. Few intracellular and extracellular hyaline globules (PAS positive) present. Some cells showed coarsely vacuolated cytoplasm. On this basis, differentials considered were SPPT, adrenocortical carcinoma, renal cell carcinoma and rhabdoid tumor. Pancreatic mass along with pancreatic tail and spleen was excised. According to cytological, radiological, gross, histological and immunological findings, final diagnosis of solid pseudopapillary neoplasm of the pancreas was made. This case is of interest due to its rarity, presence of hyaline globules and cytoplasmic vacuoles in microscopy, new molecular markers and good prognosis of patients.

Keywords:

Hyaline globules; Cytoplasmic vacuoles; Good prognosis; Pancreas

Cite the Article:

Sood N, Jindal Y. Solid Pseudo- Papillary Tumor of Pancreas - A Rare Case Report. Clin Oncol. 2018; 3: 1461.