The Effect of mi-RNAs in the Progress or Inhibition of Gastrointestinal Stromal Tumors

Shima Ardehkhani, Seyed Mohammad Amin Kormi and Amir Azizi

Department of Biology, Payame Noor University, Iran
Cancer Genetics Research Unit, Reza Radiation Oncology Center, Iran
Department of Biology, University of Zabol, Iran
Department of Biology, Islamic Azad University Tonekabon, Iran

^*Correspondance to: Seyed Mohammad Amin Kormi 

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Abstract:

Gastrointestinal Stromal Tumor is considered as one of the rare tumors in the gastrointestinal tract and is mainly found in the gastrointestinal lining and the interstitial cells of Cajal, more than half of which arise in the stomach and the rest do in the small intestine and along the gastrointestinal tract. Nowadays, the major role of micro-RNAs is known for any researcher. Our studies show that micro-RNAs, which play an interfering role in the molecular processes, can have significant destructive or very efficient and beneficial impact on all the stages from inception to final treatment. This overview article deals with the various micro-RNAs impacting on this tumor from different aspects and finally offers the best mi-RNA in terms of its properties.

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Cite the Article:

Ardehkhani S, Kormi SMA, Azizi A. The Effect of mi-RNAs in the Progress or Inhibition of Gastrointestinal Stromal Tumors. Clin Oncol. 2018; 3: 1445.