Metastatic Soft Tissue Sarcomas: A Review of Treatments and New Pharmacotherapies

Mahesh Seetharam, Kantha R Kolla and Sant P Chawla

Division of Hematology/Oncology, Mayo Clinic, USA

^*Correspondance to: Mahesh Seetharam 

 PDF  Full Text Review Article | Open Access

Abstract:

Soft Tissue Sarcomas (STS) are a heterogeneous group of rare tumors which arise from mesenchymal cells. The malignant precursor cells may differentiate into several lineages such as muscle, adipose, fibrous, cartilage, nerve or vascular tissue to name a few. There are over 50 different subtypes of soft tissue sarcomas, of which undifferentiated pleomorphic sarcoma, adipocytic sarcoma, leiomyosarcoma, nerve sheath sarcoma being more common. The treatment options for soft tissue sarcoma include surgery, radiation therapy, chemotherapy and targeted therapy. In this article we focus on approved treatments and newer therapeutic approaches for management of soft tissue sarcomas.

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Cite the Article:

Seetharam M, Kolla KR, Chawla SP. Metastatic Soft Tissue Sarcomas: A Review of Treatments and New Pharmacotherapies. Clin Oncol. 2018; 3: 1426.