Disease Free Long Survival after Stump Recurrence and Reoperation of Pancreatic IPMN with Invasive Carcinoma

Emanuele Santoro, Paolo Visca, Roberto Santoro, Pietro Mancini and Eugenio Santoro

Department of Oncology, San Camillo City Hospital, Italy
Department of Oncology, Cancer Institute Regina Elena, Italy
Department of Oncology, Cristo Re City Hospital, Italy

^*Correspondance to: Emanuele Santoro 

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Abstract:

Re-operation on malignant tumours of the pancreatic stump remaining from a previous resection for cancer is very rare. The literature reports few cases in which the tumours were mostly made up of Intraductal Papillary Mucinous Neoplasm (IPMN) sometimes associated with invasive carcinoma or adenocarcinoma (PDAC).One of those rare cases has come to our attention: a 62 year old man, anicteric, with a massive tumour of the head of the pancreas 11 cm x 7 cm x 5 cm, subjected to DCP for IPMN-MD with isolated areas of invasive cancer, misinterpreted at the beginning as PDAC. Nine years later, with markers remaining negative, it was re-operated on, a total Pancreatectomy for recurrence of the same cancer of the pancreatic stump, despite negative lymph nodes. 15 years after the first surgery and 6 years after the second operation the patient is alive, healthy, diabetic, but the disease free.The case is an opportunity, through a literature review, to discuss the biological, epidemiological, therapeutic and prognostic differences between invasive carcinoma, developed on intraductal papillary mucinous tumours, and tubular primitive pancreatic adenocarcinoma.

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Cite the Article:

Santoro E, Visca P, Santoro R, Mancini P, Santoro E. Disease Free Long Survival after Stump Recurrence and Reoperation of Pancreatic IPMN with Invasive Carcinoma. Clin Oncol. 2017; 2: 1342.