Microsatellite Instability in Chronic Myeloid Leukemia Using D17S261 and D3S643 Markers - A Pilot Study in Western India

Trupti N Patel, Manali Chakraborty and Priyanjali Bhattacharya

Department of Integrative Biology, Vellore Institute of Technology, Vellore, India
Department of Biomedical Genetics, Vellore Institute of Technology, Vellore, India

^*Correspondance to: Trupti N Patel 

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Abstract:

The incidence of microsatellite instability in chronic myeloid leukemia was investigated in a series of 10 patients confirmed by t(9;22). MSI found in clinical CML samples, directed a variation in (AC) n repeats for the markers screened. The future perspective of this study is to establish diagnostic and prognostic significance of MSI in haematologic malignancies.

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Cite the Article:

Patel TN, Chakraborty M, Bhattacharya P. Microsatellite Instability in Chronic Myeloid Leukemia Using D17S261 and D3S643 Markers - A Pilot Study in Western India. Clin Oncol. 2017; 2: 1322.