Lung Cancer Lymphatic Drainage and Bilateral Lung Transplantation

Kaoutar Ghammad, Ciprian Pricopi, Antoine Legras, Marc Riquet and Françoise Le Pimpec Barthes

Department of General Thoracic Surgery, Georges Pompidou European Hospital, Paris, France

^*Correspondance to: Marc Riquet 

 PDF  Full Text Case Report | Open Access

Abstract:

A 25-year-old female patient with cystic fibrosis underwent bilateral lung transplantation. A solitary lung nodule was discovered in the left upper lobe two years following transplantation. After thorough work-up and a biopsy proving the nodule to be an adenocarcinoma, a left upper lobectomy including complete mediastinal lymphadenectomy was performed. The analysis demonstrated adenocarcinoma with hilar and mediastinal metastatic lymph nodes, confirming that the lymphatic vessels draining the transplanted lungs restored their continuity to the mediastinum. However, the immunological response to the lymphatic system of donors is poorly understood and the genetics of cancers occurring in such lungs deserve further study.

Keywords:

Lung transplantation; Donor derived cancer; NSCLC; Lymph nodes

Cite the Article:

Ghammad K, Pricopi C, Legras A, Riquet M, Le Pimpec Barthes F. Lung Cancer Lymphatic Drainage and Bilateral Lung Transplantation. Clin Oncol. 2017; 2: 1257.