Spontaneous Regression of Primary Renal Neoplasm after Percutaneous Biopsy in a Patient with History of Contralateral Oncocytoma, Case Report and Review

Meghan Brown and Peter Langenstroer

Department of Urology, Medical College of Wisconsin, USA

^*Correspondance to: Peter Langenstroer 

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Abstract:

Background: Increased use of cross-sectional imaging has led to a significant rise in the detection of solid renal masses, the majority of which represent Renal Cell Carcinoma (RCC). Spontaneous regression of RCC is a rare, but well-documented phenomenon most often observed in the setting of metastatic disease. Spontaneous regression of primary RCC is a much more rare occurrence. Recently it has been reported that spontaneous regression can occur following percutaneous renal mass biopsy.
Methods: This article describes a case of spontaneous primary tumor regression following percutaneous biopsy in a patient with a history of contralateral oncocytoma. We also present a comprehensive review of other published reports describing spontaneous regression of a primary tumor following percutaneous biopsy.Results: In addition to our case we identified 4 confirmed cases of spontaneous regression of RCC following percutaneous biopsy. We also identified 3 cases of spontaneous metastatic lesion regression following initial remote treatment of the primary lesion, and subsequent biopsy of metastatic lesion.Conclusion: We present a case and a review of spontaneous regression of a primary and metastatic RCC after percutaneous biopsy. Though the exact mechanism of spontaneous regression is not known it is a likely cause/effect relationship with biopsy.

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Cite the Article:

Brown M, Langenstroer P. Spontaneous Regression of Primary Renal Neoplasm after Percutaneous Biopsy in a Patient with History of Contralateral Oncocytoma, Case Report and Review. Clin Oncol. 2016; 1: 1125.