Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Hematology
  •  Leukemia
  •  Endoscopy Methods
  •  Pancreatic Cancer
  •  Neoadjuvant Therapy
  •  Hormone Therapy
  •  Central Nervous System Tumors
  •  Radiological Techniques and Scans


Citation: Clin Oncol. 2016;1(1):1095.DOI: 10.25107/2474-1663.1095

Extranodal NK/T-Cell Lymphoma with Cutaneous Presentation and Fever of Unknown Origin

Bowers J, Dorsey JT, Wolanin S, Lamar Z and Ruiz J

Department of Medicine/Oncology, Wake Forest School of Medicine Health Sciences, USA

*Correspondance to: Jimmy Ruiz 

 PDF  Full Text Case Report | Open Access


Extranodal NK/T-cell lymphoma is a rare subtype of extranodal large cell lymphoma that typically involves the nasal cavity, nasopharynx, and the upper aerodigestive tract where as non-nasal NK-cell lymphoma involves any other locations of the body. Extranodal NK/T-cell lymphoma is exceeding rare in Western Countries, with most documented cases occurring in Asia. The disease often involves the skin, gastrointestinal tract, and testis. Involvement of lymph nodes, blood, and bone marrow can occur and typically overlaps with Aggressive NK-cell leukemia. Diagnosis is typically made with biopsy and immunostaining, however given the extensive necrosis seen in these tumors this often requires multiple biopsies. Typically Epstein Barr virus is present and immunophenotype shows CD56. Unfortunately this newly recognized distinctive lymphoma has not yet had a defined optimal therapy, however SMILE or CHOP and generally recommended. Prognosis is generally very poor, with the Korean Prognostic Index as the most widely used prognostic tool. Here we present a case of a 74-year-old female who presented with erythematous scalp raised patches and persistent fevers, chills, weight loss and night sweats found to have Extranodal NK/T-cell lymphoma.


Cite the Article:

Bowers J, Dorsey JT, Wolanin S, Lamar Z, Ruiz J. Extranodal NK/TCell Lymphoma with Cutaneous Presentation and Fever of Unknown Origin. Clin Oncol. 2016; 1: 1095.

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