Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Adjuvant Therapy
  •  Thoracic Oncology
  •  Brain and Spinal Cord Cancer
  •  General Oncology
  •  Haemato-Oncology
  •  Bladder Cancer
  •  Colorectal Cancer
  •  Endoscopy Methods

Abstract

Citation: Clin Oncol. 2016;1(1):1090.DOI: 10.25107/2474-1663.1090

Splenic Marginal Zone Lymphoma with Concurrent Myelofibrosis: A Case Report

Slonim LB, Geller M, Donovan V and Harris J


Departments of Pathology, Winthrop-University Hospital, USA
Departments of Hematotology/Oncology, Winthrop-University Hospital, USA

*Correspondance to: Liron Barnea Slonim 

 PDF  Full Text Case Report | Open Access

Abstract:

Myelofibrosis associated with lymphoid neoplasms is a rare occurrence with the exception of hairy cell leukemia. Its incidence in splenic marginal zone lymphoma, as we report in this article, has only been reported once in the past. We report the case of a 62 year old male with splenic marginal zone lymphoma and concurrent myelofibrosis. The diagnosis of splenic marginal zone lymphoma was achieved by a combination of clinical, morphological, and immunohistochemical findings. Increased reticulin staining of the bone marrow, cytopenias and macrocytes on peripheral blood smear supported the diagnosis of myelofibrosis. Features of primary myelofibrosis and other myelodysplastic features including associated genetic mutations were absent. Further investigation of the association between splenic marginal zone lymphoma and concurrent myelofibrosis may assist in future identification of its effect on disease course and overall prognosis, possibly playing a role in risk stratification and personalized therapy.

Keywords:

Cite the Article:

Slonim LB, Geller M, Donovan V, Harris J. Splenic Marginal Zone Lymphoma with Concurrent Myelofibrosis: A Case Report. Clin Oncol. 2016; 1: 1090.

Search Our Journal

Journal Indexed In

Articles in PubMed

NMR Metabolomics in Ionizing Radiation
 PubMed  PMC  PDF  Full Text
Metastatic Retroperitoneal Paraganglioma: Case Report and Review of the Literature
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Delivered Dose Verification for Lung Cancer Stereotactic Body Radiotherapy Using Cone-Beam CT
 Abstract  PDF  Full Text
Research Progress on the Origin and Mechanism of Liver Cancer Stem Cells
 Abstract  PDF  Full Text
View More...