The Functions and Characteristics of Hematopoietic Stem/ Progenitor Cells Derived From Umbilical Cord Blood and its Clinical Application in Transplantation

Song K, Lu Y, Tian J, Jiao Z, Wang Y and Liu T

State Key Laboratory of Fine Chemicals, Dalian University of Technology, China
Burns Research Group, ANZAC Research Institute, University of Sydney, Australia

^*Correspondance to: Kedong Song 

 PDF  Full Text Mini Review | Open Access

Abstract:

Umbilical cord blood (UCB) contains abundant portable cord blood hematopoietic stem/progenitor cells (HSPCs) that can be used as a substitute to human marrow in the reconstruction of the hematopoietic and immune system. Firstly, this article expounds the functions and characteristics of hematopoietic stem cells and hematopoietic progenitor cells and the differences between UCB HSPCs and marrow HSPCs in function, then, introduces the principle of hematopoietic stem cell transplantation and the advantages and weaknesses of UCB HSPCs transplantation. The application of UCB transplantation in the clinic are also discussed.

Keywords:

UCB HSPCs; Function and characteristic; Clinical transplantation

Cite the Article:

Song K, Lu Y, Tian J, Jiao Z1 Wang Y, Liu T. The Functions and Characteristics of Hematopoietic Stem/ Progenitor Cells Derived From Umbilical Cord Blood and its Clinical Application in Transplantation. Clin Oncol. 2016; 1: 1082.