Lymphoepithelial-Like Carcinoma Involving a Rectal Tonsil

Quatrino G, Kampagianni O, Boudreaux CW, Laurini JA and Grimm L

Department of Pathology, University of South Alabama, USA
Department of Surgery, University of South Alabama, USA

^*Correspondance to: Gregory Quatrino 

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Abstract:

Lymphoepithelial-like carcinoma (LELC) of the colon and rectum is an exceedingly rare diagnosis. We report a case of the disease in a 45-year-old female who first presented with rectal bleeding and a submucosal, mobile rectal mass. After workup, she underwent transanal excision of the mass. Pathology results confirmed LELC arising from a rectal tonsil. A rectal tonsil is defined as a prominent localized area of lymphoid hyperplasia, itself a rare finding. The uniqueness of the disease does not lend itself to standard treatment protocols. After multidisciplinary discussion, our patient was treated with adjuvant chemoradiation similar to a squamous cell carcinoma of the anus. She received treatment with 54Gy of radiation, 5-fluorouracil, and mitomycin C. She has recovered well from surgery and chemoradiation therapy without any signs of recurrence at 6 months. She continues to undergo surveillance with anorectal exams, endoscopic ultrasound, and CT scans.

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Cite the Article:

Quatrino G, Kampagianni O, Boudreaux CW, Laurini JA, Grimm L. Lymphoepithelial-Like Carcinoma Involving a Rectal Tonsil. Clin Oncol. 2016; 1: 1078.