Primary Manifestation of Marginal Zone Lymphoma in the Breast

Gloustianou G, Lakiotaki E, Riccioni O and Lazaris AC

Department of Pathology, School of Medicine, The National and Kapodistrian University of Athens, Greece
School of Medicine, La Sapienza University of Rome, Italy

^*Correspondance to: Andreas C. Lazaris 

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Abstract:

Primary breast lymphoma is a rare disease. Marginal zone lymphoma is a kind of low grade mature B cell lymphoma that arises mostly in Mucosa-Associated Lymphoid Tissue, or, less commonly, in non-mucosal sites. Its primary manifestation in the breast, as we report in this article, is an exceedingly rare entity. We report the case of a 50-year-old female, presented with the complaint of painless palpable mass in the right breast. Mammogram revealed a lesion suspicious of breast carcinoma. An open biopsy was performed and then, immunohistochemistry was carried out. The diagnosis of primary breast marginal zone lymphoma was achieved by a combination of clinical, morphological, cytogenetic and, above all, immunehistochemical findings. Neoplasms can rarely arise in unusual sites, as the primary breast marginal zone lymphoma of our case report. This awareness is a prerequisite to achieve the correct diagnosis.

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Cite the Article:

Gloustianou G, Lakiotaki E, Riccioni O, Lazaris AC. Primary Manifestation of Marginal Zone Lymphoma in the Breast. Clin Oncol. 2016; 1: 1006.