Editorial

NMR Metabolomics in Ionizing Radiation

Ionizing radiation is an invisible threat that cannot be seen, touched or smelled and exist either as particles or waves.

Published 08 Sep, 2016


Review Article

Innovative Exploratory Clinical Approaches for Relapsed and/or Refractory Metastatic Ewing's Sarcoma

Relapsed and/or refractory Ewing's Sarcoma is a devastating pediatric disease with rapid progression and oftentimes severe side effects related to generally ineffective high dose multi-agent chemotherapy.

Published 08 Sep, 2016


Case Report

Lymphoepithelial-Like Carcinoma Involving a Rectal Tonsil

Lymphoepithelial-like carcinoma (LELC) of the colon and rectum is an exceedingly rare diagnosis. We report a case of the disease in a 45-year-old female who first presented with rectal bleeding and a submucosal, mobile rectal mass.

Published 08 Sep, 2016


Mini Review

Prognostic and Predictive Values of MicroRNAs in Pancreatic Cancer

MicroRNAs (miRNAs) are small and none coding RNA that has been shown to be involved in multiple cellular processes including cell proliferation, apoptosis, survival, invasion, metastasis, and chemotherapeutic resistance of pancreatic cancer.

Published 08 Sep, 2016


Research Article

Prognostic Significance of Inflammatory Cytokines in Obese Patients with Endometrial Cancer Undergoing Robotic Versus Laparotomy Procedures

Several biological mechanisms mediate the association between obesity and endometrial neoplastic risk.

Published 07 Sep, 2016


Clinical Image

Renal Cell Carcinoma with Parieto-Occipital Bone Metastasis

One third patients with renal cell carcinoma (RCC) have metastatic disease at presentation. Eight to 15% patients present with metastases in head and neck region.

Published 07 Sep, 2016


Mini Review

Circulating MicroRNAs as Novel Potential Biomarkers in Upper Gastrointestinal Cancers

Gastrointestinal (GI) cancers are among the most lethal malignancies with extremely poor prognosis. Despite advances in the identification of novel biomarkers, only a very small number of molecular markers have been launched for the detection of patients at earlier stages or management of GI patients.

Published 07 Sep, 2016


Review Article

Sunitinib in Special Situations in their Daily Practice

In the last decade, we have witnessed a change in the therapeutic management of patients with advanced kidney cancer.

Published 07 Sep, 2016


Case Report

Misdiagnosing Hepatic Inflammatory Pseudotumor as Hepatocellular Carcinoma: A Case Report

A 61-year-old Chinese male was found to have a lesion in the left liver on routine body check-up. Laboratory tests revealed no abnormalities except for a rise in C-reactive protein (CRP).

Published 06 Sep, 2016


Research Article

Clinical Manifestations of Late Isolated Metachronous Brain Metastases after Colorectal Cancer Hepatic Metastectomy

Isolated brain metastases in patients in remission after successful colorectal cancer hepatic metastectomy are rare and not well characterized.

Published 06 Sep, 2016


Research Article

Controversies Regarding the Optimal Dose of Nab-Paclitaxel Combined With Gemcitabine in a Phase 1 Trial of Patients with Metastatic Breast Cancer

Nano-particle albumin-bound paclitaxel (nab-paclitaxel) has shown significantly higher response rates and time to progression than has solvent-based paclitaxel in patients with metastatic breast cancer.

Published 06 Sep, 2016


Research Article

Surgical Site Infection Rates in Breast Cancer Surgery at a University Hospital in Nairobi, Kenya

Background: Surgery is the mainstay of treatment for breast cancer and with it the attendant risk of surgical site infection (SSI). Breast cancer surgery, though classified as a clean procedure presents with a relatively higher rate of infection than similar operations and it remains unclear whether extended antibiotic regimes improve this outcome.

Published 02 Sep, 2016


Case Report

Tuberculosis of the Breast

Tuberculosis of the breast is an extremely uncommon presentation of an otherwise common disease especially in developing countries.

Published 02 Sep, 2016


Editorial

Molecular Diagnosis of Glial Neoplasms: A New Era

Although genetic alterations involved in the development and progression of central nervous system (CNS) tumors and especially gliomas have long been recognized, identification of a number of molecular markers in these tumors has taken the center stage with the turn of this century due to the recognition of their role as diagnostic, prognostic and/or predictive markers.

Published 31 Aug, 2016


Editorial

Advances in the Diagnosis and Management of Pituitary Tumors

At Harvard Medical School, there has been a long-standing interest in lesions of the pituitary gland. At the Brigham and Women's Hospital, we are fortunate to have a multidisciplinary group focused on this subject.

Published 31 Aug, 2016


Mini Review

The Role of Neuropsychology in the Assessment and Management of CNS Tumors

Neuropsychological testing plays an important role in the assessment and management of CNS tumors.

Published 31 Aug, 2016


Research Article

A Quantitative Assessment of Imaging Frequency on the Treatment Setup Accuracy in TomoTherapy

Image guided radiation therapy (IGRT) is becoming the standard of practice for many treatment sites and techniques, especially those involving high dose gradients such as stereotactic radiosurgery (SRS), stereotactic radiotherapy (SBRT) and intensity modulated radiotherapy (IMRT).

Published 31 Aug, 2016


Research Article

Prognostic Factors for Ependymoma Survival: A Retrospective Study

Background: Ependymoma is a rare primary brain tumor that arises from the ependymal cells of the intra-ventricular central nervous system.

Published 30 Aug, 2016


Research Article

The Arg194Trp Polymorphism in the XRCC1 Gene Have No Associated With Lung Cancer Risk: A Meta-Analysis

X-ray repair cross-complementing group 1(XRCC1) gene Arg194Trp polymorphism has been implicated in correlation with risk of lung cancer in some published studies, however, results of different studies have been inconsistent and some are totally different.

Published 29 Aug, 2016


Research Article

Ectopic Production of Β-hCG and Loss of P16 as a Predictor of Outcome in Patients with Newly Diagnosed Osteosarcoma

Osteosarcoma is the most common malignant bone tumor in children and young adults and is associated with high mortality.

Published 26 Aug, 2016




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