Commentarie

The Haploidentical Family Donor: A New Weapon against Hodgkin’s Lymphoma

The fraction of patients with Hodgkin’s Lymphoma (HL) who are not responsive to first-line or salvage therapy have a poor outcome and deserve investigation for the search of newer and effective drugs.

Published 22 Nov, 2016


Perspective

Recently, End-of-Life Issues Have Become an Increasingly Common and Prominent Part of Healthcare

Among other things, there is an emerging specialty of palliative care, which deals with some of these issues in a comprehensive manner, and seeks to ease pain and improve quality of life.

Published 22 Nov, 2016


Editorial

Radium-223 Therapy in the Set of Patients Affected by Bone Metastases

Bone-seeking radiopharmaceuticals permit targeted radiation treatment of the metastatic bone disease.

Published 22 Nov, 2016


Editorial

Cancer Immune Therapy in Clinic: 2016

According to the GLOBOCAN 2012 estimates, about 14.1 million cancer cases and 8.2 million cancer deaths are estimated to have occurred in 2012; of these, 57% of the cases and 65% of the deaths occurred in the economically developing world [1].

Published 08 Nov, 2016


Case Report

Breast Cancer Occurring after Childhood Total Body Irradiation as Conditioning for Allogeneic Stem Cell Transplantation: Case Report and Review of the Literature

Exposure to ionizing radiation during childhood and adolescence is well known to increase the risk of later malignancy, including leukemia and a variety of solid cancers.

Published 08 Nov, 2016


Case Report

Targeted Therapy’s Skin Toxicities after Immunotherapy: Skin Toxicity of Tyrosine Kinase Inhibitor Therapy Following Nilovumab Therapy for Metastatic Renal Cell Carcinoma

Anti-programmed cell death antibodies (anti-PD-1) are currently under development for the treatment of Metastatic Renal Cell Carcinoma (mRCC) and safety of subsequent treatment by VEGFR Tyrosine Kinase Inhibitors (TKI) is not known.

Published 27 Oct, 2016


Review Article

Ubiquitin-Conjugating Enzyme E2S (UBE2S), A Potential Tumor Therapeutic Target

Objective: The ubiquitin-proteasome system plays important roles in the control of numerous processes including cell-cycle, signal transduction, transcriptional regulation, receptor down regulation, and endocytosis.

Published 27 Oct, 2016


Mini Review

Voiding and Continence Problems after Radical Cystectomy and Orthotopic Neobladder in Women: A Mini-Review

Orthotopic neobladder has become the standard of care after radical cystectomy in select women with muscle invasive bladder cancer.

Published 24 Oct, 2016


Research Article

Non-Metastatic Small Cell Carcinoma of the Urinary Bladder – Clinical Outcomes from a Single Institution

Objective: This study aims to ascertain the oncological outcomes of histologically proven nonmetastatic primary small cell carcinoma of the urinary bladder in a single institution.

Published 24 Oct, 2016


Review Article

Chimeric Antigen Receptor Modified T Cells for B Cell Malignancies: An Advance in Cellular Therapy

CD19 directed Chimeric Antigen Receptor (CAR) modified T cells have recently shown dramatic results in the treatment of relapsed and refractory B cell malignancies.

Published 21 Oct, 2016


Original Research

Comparative Expression Analysis Reveals Relationships between SPINK1, TUBB3, and EZH2, and Prostate Cancer Molecular Biomarkers in the Cancer Genome Atlas (TCGA) Data

Background: Despite the recent discovery of molecular subtypes in prostate cancer (PCa) expressing or not gene fusions involving E26 Transformation-Specific (ETS) transcription factors, including ERG (for v-ets avian erythroblastosis virus E26 oncogene homolog), little is known on molecular alterations associated, and cooperative events at play during initiation and progression of PCa.

Published 21 Oct, 2016


Research Article

Delirium Improvement with Mianserin Suppositories in Cancer Patients

Delirium is a significant problem in palliative medicine, and its proper management and prevention is extremely important.

Published 21 Oct, 2016


Case Report

Oral Candidiasis Turns to Oral Cancer - A Rare Clinical Presentation

Oral carcinogens like tobacco and alcohol are well recognized risk factors associated with development oral precancerous lesions and subsequent cancer of the upper aerodigestive tract.

Published 21 Oct, 2016


Case Report

Spontaneous Regression of Primary Renal Neoplasm after Percutaneous Biopsy in a Patient with History of Contralateral Oncocytoma, Case Report and Review

Background: Increased use of cross-sectional imaging has led to a significant rise in the detection of solid renal masses, the majority of which represent Renal Cell Carcinoma (RCC).

Published 21 Oct, 2016


Research Article

The Role of Interleukin-6 and Interleukin-6 Receptor as Prognostic Biomarkers in Prostate Cancer

Background: IL-6 is known to play important roles in the growth of prostate cancer cells, activation of the androgen receptor and prostate-specific protein expression. It is reported that IL-6 promotes the growth of prostate cancer.

Published 21 Oct, 2016


Review Article

Diabetes Mellitus and Reprogrammed Glucose Metabolism in Pancreatic Cancer: Features for Clinical Translation

The reprogrammed metabolism of cancer cells underlies the shift of glucose energetics from the highly efficient oxidative phosphorylation to the less efficient aerobic glycolysis, the Warburg effect.

Published 20 Oct, 2016


Case Report

Evidence of PSMA Uptake in Brain Metastases in a Patient with Breast Cancer Her2/Neu Positive

Breast cancer is one of the most common causes of brain metastases resulting in a poor survival. The blood-brain barrier is an obstacle to the delivery of chemotherapeutics to the brain; treatment includes whole brain irradiation, stereotactic radio surgery or neurosurgery with whole brain radiation.

Published 20 Oct, 2016


Review Article

A Contemporary Review of Risk Factors for Bladder Cancer

Increased risk of bladder cancer has historically been associated with smoking and environmental exposure, however other factors have recently been investigated.

Published 19 Oct, 2016





SHARE THIS ARTICLE


Renowned Editors

MIT, John Hopkins University, Stanford University, University of Michigan...300+

Rapid Peer Review

We assure 20 days rapid peer review process

Open Access

Open Access is the free, immediate, online availability of novel research

High Visibility

Published articles are easy to find on google, google scholar and other databases