Clin Oncol | Volume 7, Issue 1 | Research Article | Open Access

Histopathologic Patterns of Soft Tissue Tumors in Hawassa University Comprehensive Specialized Hospital, Sidama Ethiopia: A 5 Year Retrospective Study

Simon Mulugeta Teferi1, Abraham Kassahun Tadele1, Selamawit Abebe Ayele1, Abebaw Amare Wodajo1 and Tesfalem Israel Korga2*

1School of Medicine, College of Health Science and Medicine, Hawassa University, Ethiopia
2School of Medicine, College of Health Science and Medicine, Wolaita Sodo University, Ethiopia

*Correspondance to: Tesfalem Israel Korga 

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Soft tissue tumors are a diverse and complex group of neoplasms having a mesenchymal differentiation. Although they are histomorphologically diverse, a majority of the time exhibit overlapping radiological features and clinical presentations. And the annual clinical incidence of benign tumors of soft tissue has been estimated to be as high as 3,000 cases per 1 million populations, whereas the annual incidence of soft tissue sarcoma is about 50 cases per 1 million populations, i.e. 1% of all malignant tumors. According to the Addis Ababa Cancer Registry, soft tissue tumors constitute the 10th and 15th common tumors in males and females respectively.
Objective: This study was to assess the histomorphologic patterns of soft tissue tumors in the pathology department of Hawassa University Comprehensive Specialized Hospital (HUCSH). Materials and Methods: A retrospective cross-sectional descriptive study was conducted on soft tissue tumors over the period from September 2008 to July 2012 E.C. All the soft tissues were received and diagnosed at the Department of Pathology in, Hawassa University Comprehensive Specialized Hospital, Sidama, Ethiopia. The Pathology reports were collected from the pathology data archives, and the variables of the study were extracted by using a data extraction sheet, and data analyses were done using SPSS version 20.
Results: A total of 239 soft tissues tumors biopsy specimens were received in the pathology laboratory with the age range of 1 to 80 years. The common age group for soft tissue tumors was 21 to 30 years 67 (28%). The male to female ratio was 1.008:1. The benign to malignant soft tissue tumor ratio was 1.57:1 and the commonest benign tumor was lipoma followed by hemangioma.
Rhabdomyosarcoma was the leading malignant soft tissue tumor followed by synovial sarcoma and generally lower extremity was the primary site affected by sarcomas. Soft tissue sarcomas had an average size of 9.49 cm ± 7.14 and benign tumors had an average size of 4.96 cm ± 5.1. The swelling was the commonest clinical presentation which was complained by 80.3% (192) of patients.
Conclusion: Benign soft tissue tumors were relatively more common than sarcomas. Lipoma was the commonest benign soft tissue tumor followed by hemangioma. Rhabdomyosarcoma was the predominant soft tissue sarcoma that was common in the first two decades of life.


Histopathologic pattern; Soft tissue tumor; Rhabdomyosarcoma


Teferi SM, Tadele AK, Ayele SA, Wodajo AA, Korga TI. Histopathologic Patterns of Soft Tissue Tumors in Hawassa University Comprehensive Specialized Hospital, Sidama Ethiopia: A 5 Year Retrospective Study. Clin Oncol. 2022;7:1951..

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