Xinyi Ding1,2, Wenji Wang1, Yingwen Bi1, Gezhi Xu1,2 and Rui Jiang1,2*
1Department of Ophthalmology, Eye and ENT Hospital of Fudan University, China
2Institute of Eye Research, Eye and ENT Hospital of Fudan University, China
Purpose: To describe three cases of primary uveal lymphoma with histopathology proven and summarize the clinical and imaging characteristics of this rare disease.
Methods: Clinical description of three patients with primary uveal lymphoma. Results: Our three cases have characteristics of primary uveal lymphoma both clinically and on imaging evaluation, except that two cases were bilateral involvement. Case 1 and case 3 showed conjunctival lesion when they presented to us, thus immediate biopsy was done and resulted in correct diagnosis with subsequent radiotherapy with favorable outcome. As for case 2, we had
ignored a crescent acoustically empty lesion adjacent to scleral posteriorly on B scan. Preoccupied with the diagnosis of metastatic choroidal tumor initially, the patient lost the opportunity to be appropriate diagnosed and managed. The eye progressively lost all vision, neo-vascular glaucoma ensued and the eye had to be enucleated.
Conclusion: Through literature review and our own experiences, we recognized that the disease has many characteristics both clinically and on imaging evaluation, timely diagnosis can achieve, so long as highly suspicious is raised and meticulous inspection be performed.
Primary uveal lymphoma; Primary intraocular lymphoma; Diagnose; Clinical characteristics; Histopathology
Ding X, Wang W, Bi Y, Xu G, Jiang R. Primary Uveal Lymphoma: Report of Three Cases with Histopathology Proven. Clin Oncol. 2022;7:1908..