Ramesh Satarkar1* and Dinesh Kulkarni2
1Department of Gastroenterology, Satarkar Gastroenterology Centre, India
2Department of Histopathology, Saurabh Histopathology Cytology Centre, India
Anorectal melanoma is an aggressive mucosal melanocytic malignancy. It is rare, and approximately one third of them are amelanotic. They can resemble benign polypoid lesions of ano-rectum. Symptoms are non-specific and include anal bleeding, anal mass, and pain. The pre-operative diagnosis remains difficult as it is not suspected due to rarity of the disease. Immunohistochemical studies on biopsies help in diagnosis. Anorectal melanoma carries a poor prognosis as it is often diagnosed late. Optimal therapy is still evolving and often surgical resection remains the therapy of choice.
Amelanotic melanoma; Rectum; Polyp
Satarkar R, Kulkarni D. Amelanotic Melanoma Presenting as Rectal Polyps. Clin Oncol. 2021;6:1861..