Shai Levi1, Rakefet Czerninski2, Stuart Fischman1 and Avraham Zini3*
1The Institute of Dental Sciences, The Hebrew University, Israel
2Department of Oral Medicine, Sedation and Maxillofacial Imaging, The Hebrew University, Israel
3Department of Community Dentistry, The Hebrew University, Israel
Objective: In order to expand the knowledge about Oropharyngeal Cancer (OPC), we analyzed in detail its epidemiological characteristics in Israel.
Methods: Data regarding 1,179 cases of OPC between 1970-2013, including patient age, sex, tumor site, type and stage, were provided by the national cancer registry. Statistical analysis was performed by IBM SPSS, WinPepi, and Joinpoint Regression Program.
Results: Mean age at diagnosis did not change. Males were diagnosed more often and were younger than females. Base of tongue was more common in older individuals. The SCC/lymphoma ratio increased from 1.1 to 3.5 in males, and from 0.6 to 1.5 in females. Lymphoma diagnosis decreased 2-fold in the tonsils, with differences in trends between the sexes. SCC rose steeply among individuals 50 Y to 59 Y and 60 Y to 69 Y, and increased more in the oropharynx site than the tonsils and base of tongue.
Conclusion: Compared to global data, it seems that OPC in Israel is characterized by lower SCC rates and no change in mean age at diagnosis and base of tongue malignancy. The relationship between the oropharyngeal tumor types and sites became apparent. Health care providers should be aware of the common tumor sites and types regarding specific age groups and sexes.
Levi S, Czerninski R, Fischman S, Zini A. Epidemiology and Trends of Oropharyngeal Cancer Between 1970-2013. Clin Oncol. 2021;6:1816..