Clin Oncol | Volume 6, Issue 1 | Research Article | Open Access

Targeted Psychosocial Care throughout Full Disease Trajectories for Better Self Efficacy in Cancer Patients: Study Protocol for a Randomized Controlled Trial

Marianne K Thygesen1,2,3*, Sonja Wehberg3, Jens Sondergaard3, Karin B Dieperink4,5, Sharaf Karim Perdawood6 and Niels Qvist1

1Research Unit of Surgical Department, Clinical Institute, University of Southern Denmark, Denmark
2Odense Patient Data Explorative Network (OPEN), Clinical Institute, University of Southern Denmark, Denmark
3Department of Public Health, University of Southern Denmark, Denmark
4Research Unit of Oncology, Clinical Institute, University of Southern Denmark, Denmark
5Family Focused Healthcare Research Centre (FaCe), Clinical Institute, University of Southern Denmark, Denmark
6Department of Gastrointestinal Surgery, Slagelse Hospital, Denmark

*Correspondance to: Marianne K Thygesen 

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Main Objective: Continuously support and coordination of psychosocial care to patients, added to usual care in whole cancer trajectories will better support patient self-efficacy, than will usual care.
Participants: Patients in the diagnostic period of colorectal cancer.
Methods: In a randomized controlled trial, 280 Danish patients will be assigned to one of two groups. 1) Usual care: Patient-centered and performed by nurses and secretaries, who can answer department specific questions. They work in separate relevant hospital units. 2) Usual care plus intervention: An additional offer of one or two nurse navigators to follow patients throughout the whole cancer trajectory. Nurse navigators offers a family-centered approach targeting patient selfefficacy
by assessment of distress and unmet needs, and intelligent integration of psychosocial care activities from hospitals, primary care, spiritual and social care, not-for-profit organizations, and families. Data is collected with questionnaires. The primary outcome measure is change in patients’ self-efficacy for cancer. Secondary outcomes are unmet needs, continuity of care, health related
quality of life and nurse navigation time spent. The adjustment of the intervention after pilot test is reported.
Conclusion: The study will be performed in primarily low and middle-income areas in Denmark, and as the intervention is complex, the underlying evidence based theories will serve for good guesses of causal processes. If positive results, we will be able to further advise the clinic in their efforts to reach a goal of optimal support in cancer trajectories.


Self-efficacy; Needs assessment; Psychosocial support; Nurse navigation; Cancer


Thygesen MK, Wehberg S, Sondergaard J, Dieperink KB, Perdawood SK, Qvist N. Targeted Psychosocial Care throughout Full 
Disease Trajectories for Better Self Efficacy in Cancer Patients: Study Protocol for a Randomized Controlled Trial. Clin Oncol. 2021;6:1815..

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