Clin Oncol | Volume 6, Issue 1 | Case Report | Open Access

A Late Relapse in an Initial Stage I Pediatric Adrenal Cortical Tumor: Histology was Right!

Alexia Gazeu1*, Cécile Faure Conter2, Frédéric Hameury3, Pierre-Yves Mure3, Daniel Orbach4, Frédérique Dijoud1 and Cécile Picard1

1Multisite Institute of Pathology, Groupement Hospitalier Est, Hospices Civils de Lyon, France
2Department of Pediatric Oncology, Institute of Pediatric Hematology and Oncology, France
3Department of Pediatric Visceral Surgery, Groupement Hospitalier Est, Hospices Civils de Lyon, France
4SIREDO Oncology Center, Institute Curie, PSL University, France

*Correspondance to: Alexia Gazeu 

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A late relapse in an initial stage I pediatric adrenal cortical tumor: Histology was right!
Stage I adrenal cortical tumor stand as tumor with good prognosis. Therefore, treatment recommendations of such benign-appearing lesions are assessed on the basis of the disease stage regardless of microscopical findings.
We present the case of a 6-year-old girl displaying an initial COG stage I disease, who relapsed at distant site about 2 years after diagnosis. Histological examination of the initial lesion was however evocative of an aggressive disease. Histological findings could have been raised as a “red flag” to discuss adjuvant therapy or strict follow-up.


Gazeu A, Conter CF, Hameury F, Mure P-Y, Orbach D, Dijoud F, et al. A Late Relapse in an Initial Stage I Pediatric Adrenal Cortical Tumor: Histology was Right!. Clin Oncol. 2021;6:1796..

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