Thomas Mulliez1,2, Thierry Gevaert1, Kurt Barbé3 and Mark de Ridder1*
1Department of Radiotherapy, UZ Brussel, Vrije Universiteit Brussel, Belgium
2Department of Radiotherapy, Institut Andrée Dutreix, France
3Department of Public Health, Vrije Universiteit Brussel, Belgium
Aims: Breast cancer patients receiving radiotherapy have an excellent oncological prognosis. However, these patients are at risk for long-term cardiovascular iatrogenic events and currently no individualized cardiovascular screening and prevention is routinely performed.
Methods and Results: By integrating data of the SCORE risk charts and radiotherapy excess ratios, we were able to develop 10-year cardiovascular mortality risk charts based on mean heart dose, age, systolic blood pressure, smoking-status and cholesterol for high- and low-risk regions in Europe.
Conclusion: Breast cancer patients are long-term survivors and individualization of breast radiotherapy and cardiovascular screening and prevention is warranted, not only based on cardiovascular risk factors but also heart dose.
Breast cancer; Radiotherapy; Cardiovascular mortality
Mulliez T, Gevaert T, Barbé K, de Ridder M. Cardiovascular Screening and Prevention in Female Breast Cancer Patients Receiving Radiotherapy. Clin Oncol. 2021;6:1768..