Journal Basic Info

  • Impact Factor: 2.709**
  • H-Index: 11 
  • ISSN: 2474-1663
  • DOI: 10.25107/2474-1663
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Urological Cancers
  •  Carcinomas
  •  Chemoprevention
  •  Gastrointestinal Cancer
  •  Adjuvant Therapy
  •  Chemotherapy and Radiotherapy
  •  Targeted Therapy
  •  Palliative Care

Abstract

Citation: Clin Oncol. 2020;5(1):1762.DOI: 10.25107/2474-1663.1762

Immunodominance as Complex Patterned Interplay of Antigen Quantitation Phenomena in Pressure Immunity

Lawrence M Agius

Department of Pathology, Mater Dei Hospital, Malta

*Correspondance to: Lawrence M Agius 

 PDF  Full Text Mini Review | Open Access

Abstract:

The basis of biology of immunodominance of antigens is defining term in the evolution of a specific antigenicity as carried forward by complex dimensions of an immune response to tumor epitopes. In such terms, immune pressure dynamics contextualize the evolving process of epitope redistribution as anergic states of non-reactivity or as terms of reference in defining such immunodominance of given antigenicity of individual tumor cells. It is further to such considerations that quantitative antigen presentation both correlates with evolution of antigen binding to the Major Histocompatibility Complex (MHC) structured molecules and with system profiles of redistribution inherent to antigen presentation on the surface membrane of both antigen presenting cells and also tumor cells.

Keywords:

Cite the Article:

Agius LM. Immunodominance as Complex Patterned Interplay of Antigen Quantitation Phenomena in Pressure Immunity. Clin Oncol. 2020; 5:1762..

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