Abdullah Şimşek* and ArzuErtem Cengiz
Department of Chest Diseases, University of Health Sciences, TurkeyFulltext PDF
Introduction: Mediastinal Lymphadenopathy (LAP) in patients with an extra thoracic malignancy is an important clinical condition that needs to be resolved. Endobronchial Ultrasound-Guided Needle Aspiration (EBUS-TBNA) is a minimally invasive procedure that can be used for diagnosing mediastinal LAP. The diagnostic utility of EBUS-TBNA in determining the nature of intra thoracic LAP in patients with extra thoracic malignancy was evaluated. Material and Method: In present study, 38 consecutive patients' extra thoracic malignancy and mediastinal LAP according to computed tomography or fluorine 18-labelled deoxyglucose positron emission tomography who underwent EBUS-TBNA between January 1st, 2018, and December 1st, 2018, were retrospectively analyzed. Results: EBUS was performed in 38 patients with extra thoracic malignancy with suspected mediastinal Lymphnode (LN) metastasis. EBUS-TBNA biopsy was achieved only in 26 patients (68.5%) but it failed in totally 12 patients (31.5%). Mediastinal LN metastases were detected in 30.8% of 26 patients who achieved biopsy. Granuloma was detected in 11.5% of patients. Most frequent LN metastasis was revealed in larynx cancer (66.7%). Conclusion: Mediastinal lymphnode metastasis was proved highest rate in larynx cancer by EBUSTBNA. Biopsy failure is still important problem in EBUS performed in patients with extra thoracic malignancy with suspected mediastinal LN metastasis.
Endobronchial ultrasound; Mediastinal lymphnode; Extra thoracic malignancies
Şimşek A, Cengiz A. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Mediastinal Lymphnode Metastases from Extrathoracic Malignancies. Clin Oncol. 2020; 5: 1705.