Clin Oncol | Volume 4, Issue 1 | Review Article | Open Access

Physiologic to Pathologic Cellular and Molecular Levels of Elusive Cell Death Programs and Their Manipulative Action

Bina Kashyap^1* and P Sridhar Reddy²

¹Department of Oral Pathology, Buraydah Private Dental College, Saudi Arabia ²Department of Oral and Maxillofacial Surgery, Buraydah Private Dental College, Saudi Arabia

^*Correspondance to: Bina Kashyap 

Abstract

The balance of cell death and cell formation in multicellular organisms is crucial to maintain proper development, tissue hemostasis and immune regulation. Any dysregulation, at cellular and molecular level, results numerous pathologies. Cell death often evolve as host defense system, in response to pathogens, eliciting inflammation with certain molecular, cellular, biochemical, morphological and physiological changes through various cell death programs. This article reviews major types of cell death (apoptosis, autophagic cell death, necrosis and pyroptosis) as a host defense factor or mediated by inflammation.

Keywords:

Apoptosis; Autophagic; Hemostasis; Inflammation; Necrosis; Pathologies; Pyroptosis

Citation:

Kashyap B, P Sridhar Reddy. Physiologic to Pathologic Cellular and Molecular Levels of Elusive Cell Death Programs and Their Manipulative Action. Clin Oncol. 2019;4:1674.