El Bez I*, Ben Sellem D, Bannour S, Mhiric A and Slim I
Nuclear Medicine Service, Institute Salah Azaïz, TunisiaFulltext PDF
There are limited reports about malignancy after 131I therapy for thyrotoxicosis. In this report, a case with papillary carcinoma is detected three years after radioactive iodine (RAI) therapy for toxic thyroid nodule. The fine needle aspiration biopsy (FNAB) had not been done before RAI therapy and. The patient underwent bilateral total thyroidectomy and central neck dissection. Physician should think that differentiated thyroid cancer can be found incidentally in toxic nodule or can be developed as a consequence of radioiodine therapy. FNAB must be performed for all the patients with hot or cold thyroid nodules before RAI therapy and all the patients taking RAI therapy should be closely followed in terms of nodule growing and cancer development.
Thyroid cancer; 131I therapy; Toxic adenoma
El Bez I, Ben Sellem D, Bannour S, Mhiric A, Slim I. Papillary Thyroid Carcinoma Development after Radioactive Iodine Treatment for Toxic Adenoma. Clin Oncol. 2019; 4: 1585.