Doege-Potter Syndrome and How a Benign Tumour Spreads: Case Report

Caldeira V, Sá T, Silva S, Murinello N, Reis JE, Bravio I, Martelo F and Cardoso J

Department of Pneumology, Hospital Santa Marta, Brazil
Department of Cardiothoracic Surgery, Hospital Santa Marta, Brazil
Department of Thoracic Surgery, Instituto Português Oncologia, Portugal
Department of Thoracic Surgery, Hospital da Luz, Portugal

^*Correspondance to: Caldeira V 

 PDF  Full Text Case Presentation | Open Access

Abstract:

Solitary Fibrous Tumors of the Pleura (SFTP) are rare tumors, usually benign. Doege-Potter Syndrome (DPS) occurs in less than 5% of TFSP and consists of refractory hypoglycemia associated with these tumors. We report the case of a 65-year-old woman with a confusional syndrome of sudden onset associated with hypoglycaemia. Chest Computed Tomography (CT) revealed a massive mass occupying almost the entire left hemithorax, which CT guided biopsy revealed a SFTP. The patient underwent surgery with complete excision of the tumor and resolution of the hypoglycemia. The pathological anatomy of the specimen identified a benign SFTP; however, 2 years later she developed a lung metastasis. SFTPs are slow-growing tumors usually benign; however a recent review reported an increased malignancy in the DPS form. The clinical course of these tumors is unpredictable and long-term surveillance is essential because of the risk of late recurrence or metastatic disease.As peculiarities of this case, we highlight the rarity of the form of presentation (with DPS), the fact of being a giant tumor of the pleura, and although histologically benign, showing a malignant evolution with metastatic disease.

Keywords:

Cite the Article:

Caldeira V, Sá T, Silva S, Murinello N, Reis JE, Bravio I, et al. Doege-Potter Syndrome and How a Benign Tumour Spreads: Case Report. Clin Oncol. 2019; 4: 1572.