Victor E. Valdespino1*, Yazzmin Ballesteros Montenegro1, Maricruz Rivera Hernandez2, German Maytorena Cordova1, Juan Landa Mejia1 and Victor Valdespino Gomez3
1Department of Oncology Gynecology, Gynecological and Obstetrician Hospital 4, Mexico
2Department of Pathologist, Gynecological and Obstetrician Hospital 4, Mexico
3Department of Oncology Surgeon, Gynecological and Obstetrician Hospital 4, Mexico
We reported 2 cases of micrometastasis in dysgerminoma; specify incidence of micrometastasis is unknown. Many times when micrometastasis is reported, the variability is constant, sometimes is reported in nodal sentinel dissection, or systematic lymphadenectomy, or with immunohistochemistry. We use the definition of micrometastasis agree with AJCC (American Joint Committee on Cancer).We show 2 patients with retroperitoneal nodal micrometastasis; omentectomy, cytology, and remainder product of surgery was negative to metastasis. They received chemotherapy (4 times BEP) with good tolerance; both are alive without symptoms. We encourage sparing surgery for endocrinal and reproductive function always. Nowadays micrometastasis is an advice to adjuvant treatment, but maybe with more reports, we can improve ower medical care, perhaps target therapy, vigilance or use a low dose of chemotherapy. We need more reports on this subject.Ower oncology gynecology group encourage systematic pelvic and paraaortic lymphadenectomy or sentinel node dissection in dysgerminoma. With all prognostic factors we can tailor adjuvant treatment in germinative tumors. In the future maybe lymph node ratio, or new classification on nodal metastasis by FIGO (International Federation of Gynecology and Obstetrics) or AJCC, could improve ower knowledge on the biological behavior of micrometastasis.
Micrometastasis; Dysgerminoma; Nodal retroperitoneal metastasis
Valdespino VE, Montenegro YB, Hernandez MR, Cordova GM, Mejia JL, Gomez VV. Micrometastasis in Retroperitoneal Lymph Nodes, 2 Cases of Dysgerminoma and Review. Clin Oncol. 2018; 3: 1560.