Clin Oncol | Volume 3, Issue 1 | Research Article | Open Access

Reirradiation in Patients with Locoregional Recurrence or a Second Primary Neoplasm within a Previously Irradiated Area after Salvage Surgery with Reconstruction Using Pedicled Flaps and Flaps with Microsurgical Anastomosis

Zbigniew Szutkowski1*, Andrzej Kawecki2, Stanisław Starościak2, Maciej Rysz2, Marek Pietras2, Andrzej Jarząbski2, Dorota Kiprian2, Anna Jankowska3 and Izabela Tyburska3

1Department of Radiotherapy, Maria Skłodowskia- Curie Memorial Cancer Center in Warsaw, Poland
2Department of Head and Neck Cancer, Maria Skłodowskia- Curie Memorial Cancer Center in Warsaw, Poland
3Department of Physics, Maria Skłodowskia- Curie Memorial Cancer Center in Warsaw, Poland

*Correspondance to: Zbigniew Szutkowski 

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Abstract

A salvage surgery is, if possible, a treatment of choice for recurrences following radiotherapy or second primary neoplasms within a previously irradiated area. A complementary radiotherapy to an area of the post tumor removal site with a necessary margin of healthy tissues after a salvage surgery is possible, although it involves a high risk of early and late toxicity. Nine patients operated using pedicled flaps or with creation of vascular microanastomoses for a recurrence or a second primary neoplasm within a previously irradiated location underwent a reirradiation. A survival of a few years in 6 patients, including a symptom-free survival in 3 patients, was achieved. The treatment toxicity was acceptable, although in one case, a necrosis of the mandible requiring surgical treatment occurred. Centers performing reirradiations must have a team of experts experienced in complex planning of radiotherapy or radiochemotherapy possess modern technical facilities and be able to carry out a complex treatment for complications related to undesirable effects of radiotherapy retreatments.

Keywords:

Head and Neck Cancer; Recurrence and Second Primary; Salvage Surgery; Reirradiation

Citation:

Szutkowski Z, Kawecki A, Staro?ciak S, Rysz M, Pietras M, Jarz?bski A, et al. Reirradiation in Patients with Locoregional Recurrence or a Second Primary Neoplasm within a Previously Irradiated Area after Salvage Surgery with Reconstruction Using Pedicled Flaps and Flaps with Microsurgical Anastomosis. Clin Oncol. 2018; 3: 1518.

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