Sibin Nair1 and Ossama Riaz2*
1Saint James School of Medicine, Anguilla
2Spartan Health Sciences University, Saint Lucia
Psoriasis is a skin ailment thought to be related to a suppressed immune system with its onset brought on about certain triggers including temperature fluctuations, infections, and stress. Psoriasis manifests as a skin rash but may also express systemic symptoms such as arthritis and nail disfigurement. As there is no cure for the disease treatment is usually found through light therapy, topical ointments, and certain immunosuppressive medications. There are five different variations of psoriasis with plaque psoriasis being the most common and highlighted in our case report. Psoriasis has a genetic component underlying its presentation with mutations along certain gene loci hypothesized to be causal factors but there is still much to be studied in terms of its genetic linkage and manifestation. Psoriasis causes an atypical growth of the epidermal skin layer due the precocious development of keratinocytes expedited by the dermal inflammatory processes involving T cells, macrophages, and dendritic cells which induce cytokines to proliferate keratinocytes. The purpose of this case report is to look at the depression in our patient being linked to inflammatory processes and hypothesize this finding by analyzing the pathophysiological mechanism.
Nair S, Riaz O. Psoriasis and Its Correlation with Depression and Body Image: Case Report. Clin Oncol. 2018; 3: 1514.