Ioannis Bougioukas1*, Mohamad Shadi Alzin1, Elke Eltze2, Ralf Seipelt1 and Hanno Huwer1
1Department of Cardiothoracic Surgery, Voelklingen Heart Centre, Germany
2Institute for Pathology, Saarbruecken-Rastpfuhl, Germany
Primary pulmonary plasmacytoma is a very rare type of extramedullary plasmacytoma and can potentially progress to multiple myeloma. Certain variability in the therapeutic management of this condition exists because of its rarity. Its presentation as a single pulmonary mass renders both surgery and radiotherapy as attractive therapeutical options. We present the 10-year-follow-up report of two cases of primary pulmonary plasmacytoma, both managed with surgical sublobar resection solely. In the first case, the follow-up was completely uneventful. In the second case, a new pulmonary mass was demonstrated seven years after the resection; however biopsy of this mass excluded both malignancy and disease progression. The actual follow-up of this patient showed no further change of the radiological finding. The possibility of existence of an amyloidoma on the old surgical scar tissue has been considered. Looking at the scarce literature, we conclude that complete surgical resection accompanied by regular aftercare is a rational therapeutical concept for primary pulmonary plasmacytoma. Performance of sublobar resection instead of a more extensive lobectomy is sufficient minimizing operative risk and hospital stay.
Plasmacytoma; Amyloid; Lung
Bougioukas I, Alzin MS, Eltze E, Seipelt R, Huwer H. Long-Term Follow-Up of Two Cases of Primary Pulmonary Plasmacytoma. Clin Oncol. 2018; 3: 1499.