Clin Oncol | Volume 3, Issue 1 | Research Article | Open Access

Could Using of Ultrasonic Grading for Axillary Lymph Nodes Improve Management of Early Stage Breast Cancer?

Ehsan Soltani1, Masoud Pezeshki Rad2, Monavar Afzal Aghaei3, Kamran Ghaffarzadegan4, Bahram Memar5, Ali Jangjoo6 and Ramesh Omranipour7*

1Department of Oncology Research, Mashhad University of Medical Sciences, Iran
**Surgical Oncologist, Cancer Institute, Tehran University of Medical Sciences, Iran
2Department of Oncology Research, Mashhad University of Medical Sciences, Iran
3Department of Epidemiology and Biostatistics, Mashhad University of Medical Sciences, Iran
4Department of Pathology, Research and Education Department, Razavi Hospital, Iran
5Department of Oncology Research, Mashhad University of Medical Sciences, Iran
6Department of Oncology Research, Mashhad University of Medical Sciences, Iran
7Department of Oncology Research, Tehran University of Medical Sciences, Iran

*Correspondance to: Ramesh Omranipour 

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Abstract

Purpose: Nowadays several studies suggested that needle biopsy of axillary suspicious nodes is more accessible than Sentinel Lymph Node Biopsy (SLNB); and thus, it is financially more beneficial. In this study, we compared using ultrasonographic features of lymph nodes alone, core needle biopsy, and SLNB for staging early breast cancers.
Methods: Participants included 50 patients who underwent axillary Ultra Sound-Guided Core Needle Biopsy (USG-CNB) from node/s larger than 10 millimeter (mm). Without considering the results of needle biopsy, SLNB, and if necessary axillary dissection were performed in all patients and the final results were compared.
Results: In all 38 (76%) cases with positive SLNB, final histology reports confirmed the diagnosis. In 24 of these patients, metastasis was diagnosed preoperatively by USG-CNB. Although only in 4 out 12 patients with normal lymph node characteristic in ultrasound, final histology revealed no metastasis. In patients with intermediate or suspicious feature, the test accuracy was more reliable. The total positive and negative predictive value of lymph node characteristic in ultrasonography were 95.7% and 40.7%, respectively.
Conclusion: Although ultrasonographic features of normal and metastatic lymph nodes can be helpful in accurate diagnosis of them, the accuracy of this modality alone is not enough to manage cancer patients with early stage breast cancer.

Keywords:

Early Detection of Cancer; Breast Neoplasms; Axilla; Neoplasm Staging; Needle Biopsy; Lymph Nodes; Ultrasonography

Citation:

Soltani E, Rad MP, Aghaei MA, Ghaffarzadegan K, Memar B, Jangjoo A, et al. Could Using of Ultrasonic Grading for Axillary Lymph Nodes Improve Management of Early Stage Breast Cancer? Clin Oncol. 2018; 3: 1486.

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