Proteomics Tools – An Update

Sachin Kumar, Vikar Gaur, Sartaj Khurana, Sudeep Bose, Manjula Kiran, Manjula Kiran and Surender K Sharawat

Department of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, India
Department of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, India
Department of Biotechnology, Amity University, Noida, Uttar Pradesh -201303, India
Department of Biotechnology, Amity University, Noida, Uttar Pradesh -201303, India
Deprtment of Biologicals, Amity University, India
Department of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, India

^*Correspondance to: Sachin Kumar 

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Abstract:

Recent advances in high-throughput genome sequencing, analytical instrumentation, bioinformatics and computational biology has permanently changed the way biology is practiced. With the evolution and progress in system biology, scientists can now study the systems comprehensively and in very fine molecular details rather than just focusing on various components of living system individually. Proteomics, commonly described as expressed form of genome, has emerged as one of the vital constituent of system biology and is being studied extensively across the globe. Unlike genome, proteome is a very dynamic and complex entity involving not only the structures, sequences, and functions of proteins, but also their abundance, localization, modifications, and interactions. Hence, proteomics can provide plenty of information for better understanding of the diversity and intricacies of the biological system. However, the analysis of these various properties of the proteome requires an equally diverse range of technologies, like two-dimensional gel electrophoresis, mass spectrometry, and protein microarrays. In this review, we provide an introduction to the field of proteomics with an aim to describe numerous tools and techniques to study proteomics.

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Cite the Article:

Kumar S, Gaur V, Khurana S, Bose S, Kiran M, Kiran M, et al. Proteomics Tools – An Update. Clin Oncol. 2017; 2: 1358.