Melanoma in Children

Sami H, Zayane A, Naqos N, Ahouissoussi C, Bendouro H, Rais H, Belbaraka R, Elomrani A and Khouchani M

Department of Radiation Oncology, Mohammed VI University Hospital, Marrakech, Morocco
Department of Medical Oncology, Mohammed VI University Hospital, Marrakech, Morocco
Department of Anatomopathology, Mohammed VI University Hospital, Marrakech, Morocco

^*Correspondance to: Sami H 

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Abstract:

Melanoma is a highly malignant skin cancer that begins in melanocytes. Many preexisting conditions increase the risk of development of melanoma during childhood. These include giant congenital melanocytic nevi, the familial dysplastic nevus syndrome, and xeroderma pigmentosum. The signs and symptoms associated with melanoma in children are similar to those in adults, as well as the histopathologic features, biologic behavior, and treatment of this tumor. Treatment is mainly based on surgery at the localized stages. For metastatic melanoma, the therapeutic options are chemotherapy, immunotherapy and targeted therapy. We report a new case of a 6-years-old child with Xeroderma pigmentosum, who was operated several times for face and back tumors, who’s morphological and immunohistochemical study confirmed the appearance of a melanoma. We also report recent data from the literature on this subject by describing the features of melanoma in children and the associated problems in order to facilitate an early diagnosis and thus an appropriate therapeutic management.

Keywords:

Melanoma; Child; Xeroderma Pigmentosum; Skin

Cite the Article:

Sami H, Zayane A, Naqos N, Ahouissoussi C, Bendouro H, Rais H, et al. Melanoma in Children. Clin Oncol. 2017; 2: 1281.