Alessandro Comandone*, Antonella Boglione, Elena Giubellino, Veronica Prati, Orietta Dal Canton, Ferdinando Garetto and Paola Bergnolo
Department of Medical Oncology, Ospedale Humanitas Gradenigo Torino, ItalyFulltext PDF
Elderly people represent more than 50% of sarcoma patients, but very few data are available on the results of treatment of this population. Aged populationis a complex group of patients because of different general conditions, presence of comorbidities, polypharmacy, and mental and social status. A Comprehensive Geriatric Assessment (CGA) can help in decision making. In our series people had metastatic or locally advanced non operable disease. One hundred thirty four patients receive done line of chemotherapy. Sixty two a second line. Monotherapy was the most common treatment. Dose reduction was necessary in most of patients. Only one complete remission was seen in first line therapy. Median survival was 7.3 months. Toxities after dose reducton was mild in conclusion elderly patients with metastatic STS have a poorprognosis. Our study empasize the need of multidisciplinary approach and to plan specific studies to define the best approach in this specific group of patients.
Comandone A, Boglione A, Giubellino E, Prati V, Canton OD, Garetto F, et al. Metastatic Soft Tissue Sarcomas in Elderly Patients: 18 Years of Monoinstitutional Experience. Clin Oncol. 2017; 2: 1231.